Trends, Opportunities and the Next Generation of Mental Health “Moonshots”

The One Mind Accelerator (OMA) has quickly become one of the world’s most influential launchpads for mental health innovation. Its alumni—including Slingshot, TownHome, Cerula Care, and others—have collectively:

• Raised over $650 million

• Served more than 860,000 patients

  …all in just three years.

In a recent feature by Steve Duke for The Hemingway Report, OMA Executive Director Carmine Di Maro highlighted key trends shaping the mental health startup ecosystem:

• Opportunities in underserved populations – older adults, maternal mental health, and high-risk professions

• Comorbidity-focused care – integrating mental and physical health solutions for better outcomes

• Innovation gaps – areas like AI chatbots and teletherapy are saturated, requiring stronger differentiation and deeper science

Di Maro also emphasizes the need for more “mental health moonshots”—bold, high-risk innovations that could dramatically improve population wellbeing. The next generation of experienced founders is well-positioned to take these leaps.

OMA continues to expand its support ecosystem:

• Expert-led growth councils to help with patient acquisition and scaling

• A new venture capital fund to invest directly in graduating startups

With its growing network and proven track record, OMA is translating innovation from lab to life, driving a new era of scalable, evidence-based mental health care.